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Re: cjgaddy post# 297295

Thursday, 05/18/2017 4:23:48 PM

Thursday, May 18, 2017 4:23:48 PM

Post# of 346228
looks like cliff has been down this road..


http://ir.perkinelmer.com/releasedetail.cfm?releaseid=963858
Pre-existing Immunity and Treatment Outcome with Anti-PD1 in Melanoma

Monday, April 18, 3:00 to 4:00 P.M., AACR Exhibitor Spotlight Theater

Presenters:
Paul Tumeh, MD, Assistant Professor, UCLA Medical Center, Dept. of Medicine Clifford Hoyt, Oncology Fellow, PerkinElmer

Abstract:
Therapies that block the PD-1/PD-L1 axis have shown significant clinical activity in melanoma and other cancers. Recent evidence has shown that pre-existing CD8 T cells infiltrates at the invasive tumor margin of metastatic melanoma are associated with the presence of the PD-1/PD-L1 immune axis and may predict response to therapy. We examined the relationship between site of metastatic disease, local immune response, and treatment outcome in patients with advanced melanoma.

and good vid.. (if you're a nerd)

http://www.sciencemag.org/custom-publishing/webinars/cancer-immunology-charting-course-forward-immunoprofiling


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