Replies to post #103292 on Anavex Life Sciences Corp (AVXL)

[OFP]

Here is the same information posted another way: "the sigma-1 receptor chaperones the functional IP3 receptor at the endoplasmic reticulum and mitochondrion interface to ensure proper Ca2+ signaling from endoplasmic reticulum into mitochondrion. However, under pathological conditions whereby cells encounter enormous stress that results in the endoplasmic reticulum losing its global Ca2+ homeostasis, the sigma-1 receptor translocates and counteracts the arising apoptosis. Thus, the sigma-1 receptor is a receptor chaperone essential for the metabotropic receptor signaling and for the survival against cellular stress."

You keep referring to this chaperone function as if it excludes others. Remember the whole "one of the main chaperone functions" discussion you had some difficulty with?

I can see I'm wasting my time though with you.

Yes...you are unable to see reality and perseverate after your points are moot.