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OFP

03/01/17 11:32 AM

#93872 RE: imho #93866

why are you discounting the subgroups



I'd have to look at my original post but I thought I allowed for the possibility that if a group truly does respond it becomes important (and I'll add hugely important).

We agree that is still a "big IF"...maybe we differ some on how much current data is pointing to that result. But I did say its worth watching.

XenaLives

03/01/17 1:00 PM

#93886 RE: imho #93866

I also expect that the reason for examination of sub groups is to design the most efficient and economical way forward in the P2/3 while increasing the chance of success.

It's good to remind oneself that this was a SAFETY & DOSAGE TRIAL with UNEXPECTED results.