Since today is the midway point (day 321 of 640) between 60% onset and the latest projected 100% onset, and the 80% onset has not yet been announced, can we start making assumptions? No, but soon...
The projected 100% onset has not been moved back yet and it appears that 60% - 80% will take more time to occur than 80% - 100%.
It is interesting because 60% - 80% have approximately 350 - 400 more patient (322 events occurred so they will no longer be in RI + some will drop out) and theoretically should accrue events quicker (due to larger pool of patients).
The argument for 80% - 100% occuring faster is aging (more events the older one gets).
Does aging (in 80% - 100%) balance out the fact that 60% - 80% have approximately 6-7% more population? Does efficacy of V come in play?
I will be very surprised if there is no announcement of the 80% onset by next week's CC.
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