The change may have already come. Biogen may have the results of the MS test and may very well be accumulating shares.
My belief if pure speculation but the one thing everyone can agree on is the trading pattern over the last couple of weeks is entirely different than previous run-ups.
You can say its because of the anticipated announcements or the Dr's great work at the various conferences but I believe its something more.
BP has smelled and tasted "the coffee." However, Starbucks (Anavex) "the Franchisor" is not for sale. When the general public gains a taste and demand for "the coffee" the Franchisor will have no trouble selling individual "Franchise Opportunities" to BPs.