Replies to post #100454 on NorthWest Biotherapeutics Inc (NWBO)

[spartex]

Canis the extra few months is for the OS results not PFS. See text from PR below.

There are 331 patients enrolled in the Trial. The Trial endpoints involve thresholds of 248 "events" for PFS and 233 "events" for OS. PFS events are primarily tumor progression (i.e., recurrence), although they can occasionally be patient deaths which occur without prior evidence of tumor recurrence. OS events are patient deaths. The PFS and OS events are continuing to accumulate as the Trial continues. The PFS events have surpassed the 248-event threshold, but the OS events have not yet reached the 233-event threshold. Based upon the pace of OS events during the last six to eight months, the Company's current anticipation is that it will be several months until the Trial reaches 233 OS events.


https://finance.yahoo.com/news/nw-bio-announces-lifting-clinical-143000739.html

[sentiment_stocks]

Still dont understand why do they need few months for primary endpoint (PFS) ? Generally they dont go back start PFS analysis again from Patient 1, mostly they have all that information except last few patients. In principle it shouldnt take more than 2-3 weeks to complete statistical analysis for primary endpoint.

Exactly. Except, going back is exactly what they are doing.

They state it pretty clearly in the PR that they are reviewing all the data, and that includes the MRI images - and I'd add - again.