Replies to post #86530 on Anavex Life Sciences Corp (AVXL)

[kld2]

good post, sokol.

[BeingReal]

You seem to be making my point..

I see serious implications in pursuing the path of "switching" a patient to an unapproved mono-therapy -- "efficacy" has not been established! Anavex would, in my opinion, be foolish to "switch" patients to the mono-therapy and announce it to the world as you say.

After all the speculation of patients being switched to mono resulting in the uptrend, I believe it's possible the uptrend is due to time on the original therapy. What say you?

[jimmy667]

As Prof McFarlane recently explained, the decisions have been made by some patients to discontinue Aricept. This was not a decision of Anavex management or the Caufield scientists running the study, again as explained by Prof. McFarlane. There was no "switching." All were on some dose of A2-73 already, some with Aricept some without. Some have decided to stop Aricept and as you point out it would have been discussed with the physician that RXed Aricept to start with.
Maybe this is why they do not call it "Mono Group" because it was not predefined that way and all those that stopped Aricept did of their own accord and at different times. Further, since it is an individual decision the scientists running the study and AVXL (understand AVXL does not run the study rather it is run by McFarlane, his superiors, and staff) can not stop any participants from restarting to take Aricept. But some have stopped of their own accord, as Prof. McFarlane stated on the record.
There has been a lot of discussion on this subject. Prof. McFarlane's testimony about this is the most important, go back and review what he said regarding this matter of discontinuing Aricept and by whom it was decided.
Some would with any confusion to try to torpedo this "Ship of Hope." Yet She sails on!
Think clearly, examine all the evidence, then make your own conclusions.
Go A2-73, Anavex and the Caulfield researchers!

[Rubyred77]

Good point about it being the patient decision to stop using a SOC approved drug. I thought I saw a video where Dr. Mac said the patients were given an option to stop using Donez or? Also, if ALL the patients didnt stop taking dual drugs, they can't say its a mono group yet.

[McMagyar]

Approved SOC is a joke!
I Side Effects are miserable.
You don't get any better, just worse slower...

You keep talking about Aricept/DZP
Like it actually provides any major benefit?

People want to live.
They risk nothing by stopping Aricept,,
What part of that is difficult to understand?
This is where we are as a people and why Anavex is not valued in multibilllions.. sad