Falconer66a post on “Anavex as a New Aspirin”.
Falconer’s post calls to mind a question I raised on this board several months ago. I’d like to re-state my observations and question now.
Over many years, I have known several individuals who passed away with Alzheimer’s. I don’t know for sure that Alzheimer’s was the cause of death in each case but they were in fact diagnosed with the disease. What I find curious is that each of them (including a high school classmate, my paternal grandmother, the wife of a close friend and my wife’s maternal grandmother) all suffered a broken bone at some point in their life. My wife’s mother who is still alive has been diagnosed with mild Alzheimer’s and she suffered a broken wrist in the past as well.
This leads to my question. While all of these cases of Alzheimer’s and broken bones may be coincidental, I wonder if any study has ever been conducted to determine if there is a correlation between broken bones or other injuries and the incidence of Alzheimer’s. My thought is that since the body is supposed to be a “closed system”, perhaps the introduction of marrow or another substance into the blood stream may be a factor in upsetting the natural balance in the body.
If they have not already done so, it should be a fairly easy task for the physicians leading the trials for Anavex to study the medical histories of the trial participants to see if there is a noticeable incidence of broken bones in their backgrounds.
This leads back into falconer’s point. If doctors were able to discover such a correlation between fractures and Alzheimer’s, and once Anavex is proved to be an effective treatment for the disease, would it not make sense that physicians begin prescribing a formulation of Anavex to patients with fractures as a prophylaxis against Alzheimer’s in the future? Yet another possible revenue stream for our therapy.
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