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McMagyar

12/19/16 12:23 PM

#84799 RE: Rubyred77 #84783

Ruby
So please understand I believe A2-73 should be made immediately available with current data.
At 5 weeks without having charts in front of me, there was a washout period and did they separate out Monotherapy at that point?

Anyway there is a placebo effect that washes out after 12 weeks so we had placebo effect and high responders affecting scores at 5 weeks.. so really you need to go to 31 weeks and average out the scores of high responders and 52 weeks and do the same. When you do this you see that the average of the other patients is really on the Sam negative slope as Aricept by itself.. now that is still ok as A2-73 has side benefits ,, but..
With super responders(full remission) we all expected everyone to be doing better..
It turns out that by Post Review of Graphs the ONLY conclusion that makes sense is that
At 52 Weeks MMSE went from 15.9 to 16.9 score, and the only way in my opinion that Alzheimers could be reversed in 19 patients at one year is the only drug that has ever reversed Alzheimer's A2-73, and since these patients were already taking A2-73 for one year, something else must have changed . Anavex has said they have not optimized dosing so that is probably not the case, the only thing that is logical is that a high number of patients stopped taking Aricept!

Which means, that there are millions of people Right Now that we may save from the ravages of Dementia/Alzheimer's if we get them A2-73!