What if the Rett's Ph2 trial starts and ends soon and A2-73 shows the kind of efficacy it showed in the murine models by stopping seizures? The Rett's trial if I recall correctly is envisioned to last 6 weeks to 90 days. Unlike ALZ where there are measurements of gradients of cognition and other markers; stopping seizures is much more binary. A2-73 will either stop them (as it did in mice) or make them much less frequent, or it will not. We will know very soon. If A2-73 shows the type of shocking therapeutic benefit in Rett's afflicted girls as it did in mice will not the scientific community and the public do an about face as to the perceived chances of A2-73 in ALZ and other CNS maladies?
A victory in the battle against Rett's would not ensure a victory in the ALZ battle but it would ensure that Anavex could continue to fight with A2-73 against ALZ and in other battles against other conditions and would allow Anavex to bring along A3-71 to fight ALZ.
The Rett's Ph2 trial will be first according to the latest strategy of the Company. This MIGHT be the watershed event the determines the fate of many suffering patients and future trajectory of Anavex Life Sciences and it's "New Paradigm" in the battles against intransigent conditions(and scientists at the BPs) like ALZ and Parkinson's.
A failure in the Rett's trial would likely mean a long and lonely fight for the future of Anavex compounds.
Missling and AVXL will fight the Rett's battle first! Why would they do this if they thought there was a chance of a failure?
If they thought it might fail in Rett's and they were a scam company as AF and J Fin espouse would they not just do a long ALZ trial first so they could in the words of AF and the other short shills "continue to dupe investors all the while." No, they will fight the Rett's battle first, win it, forever silence the critics and attract new and powerful allies for the battles against ALZ and Parkinson's.
Engaging the Rett's trial first is the very definition of fearless
confidence. Think about it!
Remember the words of Christopher Missling spoken in Washington DC last year when asked why he felt Anavex can succeed where BP had failed. "Because we think differently and have NO FEAR!"
Go Avanex Life Sciences!
Good Luck to all longs and to the brave men and women of Anavex!
Merry Christmas
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