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marthambles

12/11/16 5:19 PM

#206880 RE: poorgradstudent #206879

genisi

12/11/16 6:02 PM

#206882 RE: poorgradstudent #206879

I've been looking at light chain amyloidosis where the sink hypothesis seems to have *some* relevance... a benefit on target organ function

Organs but not the brain right?
In AD the “sink hypothesis” assumes equilibrium between peripheral and brain a-beta, so perhaps the "sink" is not as relevant in cns amyloidosis.