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poorgradstudent

12/12/16 12:00 PM

#206910 RE: genisi #206882

amyloidosis:

Organs but not the brain right?
In AD the “sink hypothesis” assumes equilibrium between peripheral and brain a-beta, so perhaps the "sink" is not as relevant in cns amyloidosis.



Yes. That's what I was trying to say, albeit poorly. The sink hypothesis may not be universally bunk for amyloidosis, but have situational validity.