First off, no one knows the RRR for Reduce-It first review by DMC, but the DMC. As noted by other posters, three other CVD trials noted - including 'Jupiter' continued after DMC review even with high RRR.
I believe Vascepa is mirroring these other trails with high RRR. Jelis is probably not an ideal reference for effects of EPA over time, compared to some other small trials we have seen. The Japanese patients started with high levels of EPA in there blood stream from the start of the trial.
After two years on Vascepa I have lost my belly fat, down to 177 from about 185 or so a couple of years ago.
Controlled wait loss? I still eat a lot...