If we saw more unequivocal proof of effect in any of those areas, i'd be buying now. The only 1/2 way convincing proof we have is in short term ALZ and that's still a tad shaky. That a single drug could address all of those indications effectively is improbable . Usually such sweeping claims come with quackery and that has me nervous. I think that an excess of expectation lead to our present low PPS.