I've sent similar requests in the past with no positive results. I have a lot of skin in AVXL, so it pains me to wonder why. Don't we own a significant piece of the company? Noting that they spend twice as much on administration and employee stock benefits than R&D.....with a tiny R&D staff. .And seeing that they aren't much interested in keeping shareholders informed unless they want to raise more $.... All this continues to make me nervous. Why haven't we heard even anecdotal reports about the condition of the early test subjects? Where's our big Ph 3 trial? Is management just stringing us along as long as possible? For the first time, i've managed to not add more shares when the PPS is down. I'm a cynic by nature and feel it's necessary to ask questions of all my holdings.