Replies to post #74281 on Anavex Life Sciences Corp (AVXL)

[frrol]

Yes. There have been literally hundreds of promising AD drugs whose backers showed "proof" that there's was different. Nothing like a robust advanced clinical trial to get actual proof. Our Phase 2A is small but it is relatively long term. This is its saving grace, and the fact that we are seeing some anecdotal strong response in a sub-population (one of two possible) is reason for hope.

Nice that MacFarlane and Missling say they think the drug works but they all say that. The market is not fooled. They require proof.

[XenaLives]

Enbrel has very toxic effects. You linked to a 2008 article, has Enbrel been approved for Alzheimer's?

Perhaps the risk outweighs benefits. Trade MS for improved Alzheimer's symptoms anyone?

Side Effects of Enbrel®

Enbrel® is NOT a drug one would take unless it is critically needed. That is because when administered systemically, it increases the potential risks of infection, low blood counts, lymphoma, demyelinating nerve disease, eye inflammation, congestive heart failure, and death.73 The long-term side effects are not known when Enbrel® is administered primarily to the brain, as is being done in this anti-Alzheimer’s treatment.

Written informed consent has been obtained from all these Alzheimer’s disease test subjects (or their family members) warning them of these potential risks. The rationale in accepting known and unknown side effect risks is that Alzheimer’s disease is a uniformly progressive and lethal disease. There is no other therapy that so rapidly and effectively reverses the clinical course of the disease.

http://www.lifeextension.com/magazine/2008/8/novel-drug-therapy-immediately-reverses-alzheimers-cognitive-deficits/page-01