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XenaLives

08/23/16 9:14 AM

#74096 RE: Amatuer17 #74094

Flawed analysis - we don't have recent data....


However recent data showed that - it is safe but may not be as effective as was touted - further in presence of D it seems ineffective (no conclusion)

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camk

08/23/16 9:25 AM

#74097 RE: Amatuer17 #74094

My take is that AD may actually be on the back burner and that their attention has shifted to RHETTS and Parkinsons. Both trials would certainly be HUGELY shorter than the eventual AD trial

I'm all for effectuating the S3 and bringing in approximately $9m. This is very minor dilution and gives them a runway well into next year.

jmho
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McMagyar

08/23/16 6:09 PM

#74116 RE: Amatuer17 #74094

wrong:
the ONLY data that really MATTERS is SAFETY: PERIOD!
The Efficacy Data is Pooled and you can tell very little..
ACCEPT..You can tell that the POOLED Data is BETTER than
BASELINE Alzheimers..Regardless of your stance on Data..
A2-73 is 100% better than Nothing!
The adaptive Phase 2s is designed to find MTD: Check 50 Mg, PK , check seen at 3Mg but 14 mg, more noticeable.
Look there are lots of Sigma 1 Agonists..but nothing like this.nothin!

All the positives are BILLION DOLLAR GRAVIES, not YEARS AWAY, but MONTHS,
because with A2-73 SAFETY profile and ALL the ANECDOTAL BENNIES,
the SECOND A2-73 becomes available for ANYTHING..
and I meand ANYTHING..CONSUMERS are going to BLOCKBUSTER
this Drug into the STRATOSPHERE..
Parkinson's, Depression, Insomnia, Alzheimrs delay..anti-convulsive,
Sigma 1 bennies not yet accounted for ..but..I believe Eyesight and heart issues will definitely come into play..
Any single ONE of these IND's makes AVXL a Multi-Billion Dollar Cash WOnderDrug..
But Anavex will just keep adding Multi-Billion Dollar IND's like
Country Sausage White Gray over Butter Milk Biscuits..The Good News will just keep coming IND after IND.
No one is waiting years..FDA will have A2-73 approval sooner than you think! Powerful People need drugs to brother..Powerful people don't want to die of Parkinsons or Alzheimers..You think THEY won't make FDA get them A2-73?
We will have A2-73 available by end of 1st Quarter of 2017!
Maybe even by end of THIS YEAR.
IF and that is a big IF, A2-73 keeps it's safety profile clean, squeaky,
and no additional side effects of any note are found..
A2-73 may be available because of and BY PUBLIC DEMAND even sooner in some countries..say in
Australia...A Painting or a Song speaks to people in a very basic language. LIFE is GOOD!
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123tom

08/23/16 6:45 PM

#74119 RE: Amatuer17 #74094

...and now 3 days of suppression....

I have to agree with your evaluation 'Amateur'

from the chart picture and the price action pattern developing, its saying just about as much.
a slowing down,a suppression, and a grinding ,grinding away HERE ?? at 3 dollars? Even after a decent bounce from the 2.91 bottom to 3.87, that was a fair rally bounce but now....no follow thru at all. instead we just saw 3 days of suppression, where even the small rallies that should at least start to retest the 3.80 ,maybe 4 dollar zone, are being suppressed and delayed. held down at 3.20 area... some can call it basing and maybe its ok that we at least dont see continued plunge to the 2.80 and the 200ma,small consolation so far but hey anything that isnt disasterous is ok right? but when you look at the chart and price action, from the last 3 weeks, ok, you get the slam down from 7.80 to 2.91 and then you start to get a good bounce that says 2.91 is a bottom to buy, folks bought it , big money stepped in there, and we get a rally of 1 dollar. then we get a real pullback to 3.14, then we start to see the next rally begin....but now in the last 3 or 4 days ...It Stalls out and slides sideways and down like a heavy shoe is stepping on it to suppress it , and prevent the next rally. IF AVXL is being controlled by the Big Money Powers, then they are showing us they intend to stifle the rally,and thats what we see in the last 3 days.wallowing here at 3..20 They havent slammed it down to 2.90/2.80 yet. but they are not allowing or generating any continued rally up the stair steps, 3.50 is the next one. you can see them on the chart, 10 cent steps, but the central stations are 3.50/3.60,then 3.80 to the 4 dollar/4.10 target.
and thats just the next rally wave, AVXL wants to be sliding along the 4 dollar zone ,not 3.20 and greater target still remains the 4.40-4.80 area and testing 5 dollars . All this price suppression at 3.30 is just that ,a capping to suppress and intentionally keep AVXL down.What short players would sell at 3.32,seriously ? what force of power would cap the rally at 3.58 and now 3.32? Maybe they do plan to plunge it lower from here and target the 2.80. a few more days like this could begin the next slam down



Of course I could be seeing the chart wrong, but if what I see is on target, then we need to see a rally jump soon, this week, to at least retest 3.60 and better would be 3.80. AVXL can not afford to stay stuck here at 3.25 area,or it risks getting slammed down to test the 200ma at 2.80.
I believe all we can do is watch what the Powers in control of price Intend to do. and right now, it appears to me that they are not allowing any rally to the technical targets 3.50/3.60/3.80/4.00/4.10/4.30/4.40 are the main target steps overhead. and the first big rally bounce we got from 2.91 to 3.87 was hopeful, and the pullback to 3.14 That Held ok, was hopeful enough....but now, in the last week of trading, AVXL is acting like its exhausted and cant rally anymore. I believe price is totally controlled by the big money powers,and it does what they intend for it to do. IF they want AVXL to rally to 5 dollars it certainly would be heading that way in the current pattern, coming off the first rally wave that reached 3.87, and coming off the wave 2 pullback that "Held so far" at 3.14...its time for the next technical big rally to target at least 4 dollars,and a finishing 5 wave to complete around 4.80....The technical tracks on a chart pattern that has been crafted so far "should" be doing this, continued rally. Otherwise, I suspect they may be planning another plunge to target the 200ma at 2.80