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chinatown1980

08/15/16 12:24 AM

#69891 RE: 791branko #69889

Thanks Branko. With regard to progression free survival, which is the primary endpoint for this trial, it seems there should be a statistically significant difference between the treatment and control groups if the treatment is effective. The placebo group represent the patients "who didn't get anything" (before they crossed over). So why weren't the differences "bigger"? Well we know from Dr. Bosch that "pseudo progression wrecks havoc on clinical trials", so that's one possible reason. I'm looking for any other plausible explanations.

maverick_1

08/15/16 8:09 AM

#69900 RE: 791branko #69889

Been discussed ad naseum for the whole duration FOUR MONTHS of that poster's reincarnation from ReadyforBlueSkies to Chinatown. But apparently it's a new day for some here a la AF.