OK, Ex, did you actually read the studies you posted
None of them uses adjuvant hormonal therapy in combination with downstream 1.0 inhibitors.
Not one.
Yes, there is one study with HER2+ positive receptor breast cancer, but no mention of Herceptin (which is a limited field anyway as only 20% of breast cancers express this gene receptor.)
Ditto for all the others. No tamoxifen, no Xtandi. No Herceptin.