Can not watch/listen right now, but if I understand your point I agree.
When people say "respond" they mean shrinking the tumour. But IO agents might very well be poor against bulk tumour while effective at preventing mets.
I think we need a rethink on what we mean by saying "respond to" a treatment.
I would not hold it against DCVax if it is poor wrt recist response rates, just like I do not hold the low response rates against PD-1s either.