Replies to post #85653 on Amarin Corp Plc (AMRN)

[HDGabor]

K-

??? When I said that "sample size has no relevance"? We talked about pt yrs. Meanwhile the two have relation, the "affect" isn't a same.

Of course, sample size has relevance: the primary relevance is the duration of the study. Larger size -> faster to reach the required event number. If we have 16k enrolees, 2 times faster -> the interim should be happened more than a year ago. The average follow-up (it is app. 3 yrs now) is more relevant than total pt yrs (meanwhile does not affect the result directly).

As an example: if placebo rate is 40% / yr and V is 0% / yr, we have less than 8,000 pt yrs only ... and the result isn't "knock it out of the park", it is the second "Moon" ... with 8,000 pt yrs only

To avoid any doubt: sample size does not affect efficacy.

Correction to my previous post: take two courses.

Best,
G