Replies to post #81568 on Amarin Corp Plc (AMRN)

[BioChica]

Sound about right, the are not going to design a trial with subsets that will be under powered.

[sts66]

I see your point about the mathematical numbers of patient in different subgroups assuming equal distribution - too small to have an impact, won't bother to poke with a "but what if?" scenario :>)

I think this one from your list is the biggie we're after, because it's the Holy Grail - preventing risk factors from progressing to established CVD:

diabetes and at least one additional risk factor for CVD, but no established CVD (CV Risk Category 2), app 2,400 patients;

P.S. Is anyone besides me feeling pretty giddy right now over FDA finally awarding us NCE!?!