Replies to post #264018 on Avid Bioservices Inc (CDMO)

[biopharm]

..Adam17 with direct links to exposure of flipped PS...and iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling

Those PS receptors..... may as well simply target flipped PS instead of just a limited number of receptors but no one can do that except Peregrine Pharmaceuticals

Breaking down cancer cell defenses
Inhibiting membrane enzyme may make some cancer cells more vulnerable to chemotherapy

Date:
May 21, 2016
Source:
University of Pennsylvania School of Medicine
Summary:
The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers. Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first-line treatment for cancers (mainly lung) driven by a receptor called EGFR.

The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers.
...
..

https://www.sciencedaily.com/releases/2016/05/160521071209.htm