Replies to post #62412 on Anavex Life Sciences Corp (AVXL)

[georgejjl]

Similar positive MMSE score effect and no notable difference between ANAVEX 2-73 alone and ANAVEX 2-73 with donepezil (ANAVEX PLUS) were observed.

http://www.anavex.com/?news=anavex-announces-two-year-clinical-extension-study-of-anavex-2-73-and-presents-phase-2a-dose-response-analysis-at-aat-conference

Actually, there is a small improvement probably more additive than synergistic to ANAVEX PLUS compared to Anavex 2-73.

Slope = 0.055 95% CI = 0.012-0.098 (AV2-73 alone)
Slope = 0.155 95% CI = 0.019-0.029 (AV2-73 with 10mg donepezil)
Positive slopes with increased ANAVEX 2-73 dose

See slide 18

http://www.anavex.com/files/2016-03-12_AAT_Anavex_Presentation_2016.pdf

Good luck and GOD bless,

George