An open question is whether a higher pretreatment absolute lymphocyte count necessarily means more likelihood/chance there would be significant overlap between peripheral blood lymphocytes and tumor infiltrating lymphocytes -- and thus even higher likelihood of survival correlation when treated with an immune activating/reactivating immunotherapy like DCVax-L.
If so, then that would go a long way toward explaining why it seems everyone is living longer than expected. IMHO.
Ok, I see where you are coming from and completely agree. Lymphopenia with regard to Tregs is a good thing and Tregs may be slightly delayed in their rebuild which would give DCVax-L a little time to work with. Thanks for your thoughts.