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flipper44

04/26/16 12:49 PM

#59750 RE: flipper44 #59745

So Doc,

An open question is whether a higher pretreatment absolute lymphocyte count necessarily means more likelihood/chance there would be significant overlap between peripheral blood lymphocytes and tumor infiltrating lymphocytes -- and thus even higher likelihood of survival correlation when treated with an immune activating/reactivating immunotherapy like DCVax-L.

If so, then that would go a long way toward explaining why it seems everyone is living longer than expected. IMHO.

What do you think?

Doc logic

04/26/16 1:00 PM

#59753 RE: flipper44 #59745

flipper44,

Ok, I see where you are coming from and completely agree. Lymphopenia with regard to Tregs is a good thing and Tregs may be slightly delayed in their rebuild which would give DCVax-L a little time to work with. Thanks for your thoughts.