Replies to post #60230 on Anavex Life Sciences Corp (AVXL)

[Diamondhands45]

These were all based on small enough statistical changes so as to allow for the placebo effect. The other name for that would be the drugs don't work. However, 2-73 has far and away been the earliest and most parabolic therapeutic effects in history of alz so far. Every one of those cited had only slowed decline and minimally. Any scientist who knows statistics understands that when the effect is minimal, you can call it anything you want. Placebo vs ineffective. For me the plaque reducing mechanism repeatedly and consistently failed. It worked a little for a few weeks and failed. Luckily for Avxl and its patients and investors, the mechanism is far upstream and the stat sig is better than anything ever far. So people who argue that the placebo effect has little place here are correct both pragmatically and statistically so far.

In addition, no drug EVER has reversed alz. And returning to the piano or golf is quite simply not possible scientifically with placebo.

Regards. Thanks for the article. But quite boring for scientists.

Regards

[JB3729]

Thanks for posting that article.

Obviously, the bottom line is this -

On the whole, though, Schneider thinks that all the sources of statistical noise are likely to obscure only the weaker treatment effects. “If we had markedly effective drugs, we would see through some of these limitations,” he says.