LP is a shareholder of some significance, and the decisions she made regarding establishing tight control over the manufacturing, whether you agree or not, were likely made with the success of the trials in mind. When patients interests are put first, and the choice of receiving a safe and effective treatment over one that is not as safe or effective, the market will surely reward the decision to develop products with the highest efficacy, and shareholders will be rewarded. It just might not happen on the timetable that some would like.