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Stillwell888

04/12/16 10:32 AM

#58772 RE: chinatown1980 #58769

No vaccine has received FDA approval for GBM and a few have notably failed. However, according to both Dr. Linda Liau and Dr. Robert Prins DCVax-L is effective against mesenchymal subgroup.

For someone who is a quick learner and does his homework this is rather fundamental point to have missed.
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GoodGuyBill

04/12/16 12:56 PM

#58796 RE: chinatown1980 #58769

Doc, in all fairness, we don't know yet if DCVAX is any more effective than other vaccines. But that is what we are all hoping for.



Not everyone is hoping for the effectiveness of DCVax.
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Doc logic

04/12/16 1:03 PM

#58798 RE: chinatown1980 #58769

chinatown1980,

In all fairness, method A and method B in Direct showed a clear distinction. This evidence mark a clear and recognizable benefit and the MO is in accordance to what I expected biologically to happen. I had an outside hope that immune memory might have a chance with one or the other methods but the muted effect of inappropriate spacing and amount was too much to overcome in most patients. That is being corrected. The only doubts I have is about when we will have full validation from the scientific community at large. The PI Dr. Subbiah already commented on his longer term expectations for this treatment.