The big boys already provided validation with their own DC research. Pyrrhonian gave us the proof with the graphs he put up trying to show DCs alone are usually not that effective at doing anything but provide an immune response and minimal survival benefit. DCVax-L is different in and of itself compared to other DCs, though, and the injection among and schedule are different than what has been used before. This is why the big boys want to play in the NWBO sandbox which in combo terms is theirs alone by patent pending.