Is it possible we now know the composite rate of the Reduce-it study ?
Consider, as of Feb. 25 2016:
"Approximately 20,000 patient years of study experience have been accumulated...over 99% of the approximately 8,000 patients targeted for enrollment in the event-driven REDUCE-IT study have been enrolled
and
Based on historical event rates in the study, Amarin expects to attain 60% of the target aggregate number of primary cardiovascular events during the first half of 2016"
8000 x .25 (three more months) yields ~22,000 patient years by May 25
22,000 x 4.4% composite rate = 968 events by ~May 25.
The only question is the placebo rate.
If the placebo rate is 5.2% that would mean a 31% RRR; If greater than 5.2% then a greater RRR.