I question whether doctors will be able to have the discretion to deploy it as a first line treatment once it is approved. If DC Vax Direct can demonstrate stable disease or even better, partial or complete response once the full treatment regimen is able to be used, why would anyone wait until they were stage 4 and failed all other treatments? Why not use it as a first line of defense once proven safe and effective?
With GBM, there is synergy, although I believe that radiation has been shown to have less positive impact than Temodar. Radiation may be hurting based on earlier studies I saw posted on this ihub.