Replies to post #139669 on Innovation Pharmaceuticals Inc (IPIX)

[ericseb2003]

Once again, our biggest catalysts are mid-year loaded, so getting this unavoidable and long overdue correction out of the way now (i.e., biotechs already down -40% from high), bodes quite well timing wise for us to be in a much more healthy environment when our big ticket news items hit the wires May through summertime!

Would be disastrous for all the good news we've been waiting for to have been released right before a 40%+++ correction was to hit our sector, a major headwind we'd have to had gone against. Now, good chance we get the tailwind of a post crash recovery during our strong news cycle to carry us to even higher heights!!!

[To infinity and beyond!]

As prev noted on this board: just read about the lifespans of your red and white blood cells. Neutropenia esp has proven to be a sticking point for many many drugs chemo and otherwise, incl the MDM2 drugs.

Giving K more frequently MAY have toxicity we do not know about yet- it has never been given 3x week, right? Your bone marrow has plenty of time to recover if it takes a hit with a short half life drug given once a week. Maybe 3x week no impact.

But maybe a real impact on cells whose life spans are VERY short/produced in massive numbers every hour/day. Even if DFCI has shown NO decrease in neutrophils with highest doses so far, it still does not mean K will have no adverse effects as dosing changes

[frrol]

That is not really correct. 'Xmg once a week is safe' does NOT really equal 'Xmg three times a week is safe'. This is what PK/PD analysis helps to determine, and ultimately the proof is when the more frequent dosing is actually performed. Everyone is pretty confident it's safe - including the FDA which is giving approval to try it - but it is not a foregone conclusion.