Replies to post #50716 on Anavex Life Sciences Corp (AVXL)

[sokol]

Excellent, George. A scientific basis for Anavex therapy to be used to treat many diseases besides Alzheimer's, Parkinson's, etc.

[georgejjl]

How many diseases and/or conditions can be treated by Anavex?

"...A possible therapeutic mechanism for sigma-1 receptor agonists in neuropsychiatric diseases. Stimuli such as oxidative stress, inflammation, disturbances in Ca2+ homeostasis, and enhanced expression of normal and/or folding-defective proteins may lead to the accumulation of unfolded proteins, a condition referred to as ER stress, and, ultimately, to the development of neuropsychiatric diseases. Cognitive impairment is shown in patients with a number of neuropsychiatric diseases including schizophrenia, major depressive disorder (MDD), bipolar disorder, generalized anxiety disorder (GAD), panic disorder, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), post-stroke depression, and delirium...."

http://www.sciencedirect.com/science/article/pii/S1347861314000176

Good luck and GOD bless,

George