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There is a lot of data on Sovaldi, so I would guess that it would be a reasonable place to start a proof of concept.
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Understood. Since POC studies with Sovaldi have been done by so many companies, analysts/MDs have concluded that no effective regiment can be without it or another nuke. In order to break that entrenched belief, ABBV is doing the P3 GT3 study(ENDURANCE 3). I think ENTA should do the same. Doing a POC without Sovaldi will show what EDP-494 can do wihout the gold standard.
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