Wed, 16 Dec 2015 13:30:00 GMT ~ Regen BioPharma, Inc. Identifies Small Molecule Drug Candidates Targeting Its Proprietary Immune Checkpoint NR2F6
[PR Newswire] - Regen BioPharma, Inc., (RGBP) and (RGBP) announced today identification of a series of compounds that have been identified by biochemical testing which interact with the Company's newly identified immune checkpoint NR2F6. This is the first of a series of steps in developing small molecules which the Company plans to use as a basis for creating "a checkpoint inhibitor pill." Previously, the Company reported that the use of gene silencing of NR2F6 leads to induction of cancer stem cell differentiation, a process that renders malignant cancer cells benign. "We are optimistic that these initial positive data will lead the way forward into what we hope will be a new generation of immune stimulatory cancer drugs: Orally-available agents that will on the one hand unleash anticancer immune responses and on the other hand directly reprogram cancers rendering them less malignant," said Harry Lander, Ph.D., President and Chief Scientific Officer of Regen.
Tue, 15 Dec 2015 13:30:00 GMT ~ Regen BioPharma, Inc. Receives FDA Clearance to Initiate Clinical Trial of HemaXellerate
[PR Newswire] - Aplastic anemia, a condition that occurs when the body stops producing enough blood cells, is a potentially fatal disease of the bone marrow that leads to bleeding, infection and fever. Severe and very severe aplastic anemia can have a mortality rate of greater than 70% and are considered a hematologic emergency. Current treatments include blood transfusions, immunosuppression and stem cell transplantation.
Link: http://www.otcmarkets.com/stock/RGBP/company-info Ticker: $RGBP OTC Market Place: OTC Pink Current CIK code: 0001589150 Company name: Regen Biopharma, Inc. Incorporated In: NV, USA
Business Description: We are a majority owned subsidiary of Bio-Matrix Scientific Group, Inc, a Delaware corporation. We intend to engage primarily in the development of regenerative medical applications which we intend to license from other entities up to the point of successful completion of Phase I and or Phase II clinical trials after which we would either attempt to sell or license those developed applications or, alternatively, advance the application further to Phase III clinical trials. The primary factor to be considered by us in arriving at a decision to advance an application further to Phase III clinical trials would be a greater than anticipated indication of efficacy seen in Phase I trials.Less >>
$RGBP share structure
## source: otcmarkets.com
Market Value: Not Available Shares Outstanding: Not Available Float: Not Available Authorized Shares: Not Available Par Value: Not Available $RGBP extra dd links
~ RGBP = IT IS VERY CLEAR =.The~JV~thru~NIH~is~COMPLETELY~FUNDED!! ;-)
That is Why the 8k is such HUGE New$!! ;-)
RGBP,, NCATS, NIH, arRre NOT Allowed to disclose the Information of How much Money this is,, or how much Costs arRre!! IMO,, its final Costs arRre not completely known,, but make NO Mistake,, this Collaboration is COMPLETELY FUNDED!! ...and for up to 3 Years!! ;-)
Background 1. NCATS and Collaborator want to collaborate on a research project; and 2. NCATS and Collaborator want to transfer between the laboratories of their investigators, during the term of this Agreement, confidential information and proprietary research materials required to conduct the research project.
Terms and Conditions
Article 1 DEFINITIONS 1.1 “Confidential Information” includes scientific, business, or financial information pertaining to the Research Project (defined below) that is designated as confidential by Provider (defined below). Confidential Information does not include information that: (i) is in the public domain other than as a result of a disclosure by Recipient (defined below) or any of Recipient’s representatives in violation of this Agreement; (ii) was in the possession of Recipient before disclosure by the Provider; (iii) is acquired by Recipient from a third party having no obligation of confidentiality to Provider; (iv) is hereafter independently developed by Recipient, without reference to Confidential Information received from Provider; or (v) Provider expressly authorizes Recipient to disclose.
...and there is Money to be Gained from the HUGE JV!!! ;-)
On December 15, 2015 Regen Biopharma, Inc. (“Regen”) entered into an agreement (“Agreement”) with the National Center for Advancing Translational Sciences (“NCATS”), which is a component of the National Institutes of Health (“NIH”), an agency of the U.S. Department of Health and Human Services
Inventions made in the course of the Research Project will be owned by the Party employing the inventor or inventors. Inventions that are invented jointly by employees of both Parties will be owned jointly.
The Parties, moreover, agree to enter into an inter-institutional agreement with respect to joint inventions, which shall authorize Regen to have primary control and responsibility for any patenting and commercialization activities and shall be negotiated in good faith based on the respective parties’ contributions to each Joint Invention.