Also George Dr. Maurice, a sigma 1 world expert, and co-lead most of the 273 pre-clinical trials, speaks very highly of both 141 (little discussed) and 371 as both very high in future potential!!!!!!
1. That was then, this is now 2. They used female 3xTg-AD mice and male Wistar rats, not humans 3. They mixed their drug injections with radioactivity 4. Not same drug mechanism as AVXL ,,, AT ALL 5. Dr. Fisher’s focus back in the day: novel cholinergic treatments with a focus on muscarinic and NICOTINIC agonists. http://www.jbc.org/content/284/6/3793.full.pdf 6. They didn’t couple their molecule with donzipel for synergistic effect 7. Script parrots? Maybe early experiments were similar. Why rewrite a book? 8. Torrey Pines Therapeutical had many phase I trials; not much more, and the CEO dubiously moved on taking TP clients with him 9. Anavex 3-71 *don’t you mean A2-71* regarding AF710B with AF267B: Sorry you lost me :/ 10. Same inventor. Yes, Dr. Fisher is the conduit. He’s not too old a scientist to learn from experiments. He has surpassed his Torrey Pines association. They broke apart http://www.alzforum.org/papers/m1-muscarinic-agonists-target-major-hallmarks-alzheimers-disease-update 11. Dr. Abraham Fisher is from Israel - The Weizmann Institute of Science in Rehovot - one of the world's top-ranking multidisciplinary research institutions (Israel’s DARPA) 12. The objective at Torrey Pines was trying to clear the Aß out of the brain and work on immunization…15 separate attempts failed. We know Anavex isn’t doing that. Can’t get rid of old plaque & immunization too far off 13. Dr. Fisher has had other successes 14. Back then (2006-2008) they weren’t able to cross the blood-brain barrier …Scientists have now solved that issue 15. Wider markets are now waiting for this drug (or powerful antioxidant). Besides Parkinson’s, there is adult Down’s Syndrome and childhood ADHD & ADD…many more who need the positive mechanism of AVXL2-73. Could be a Genius Pill for the regular Joe like us 16. Perhaps Dr. Fisher, et al, have finally advanced and come into their own? It’s a gamble in the stock market 17. Man walks into a bar. Says G-d just told me how to help people with Alzheimer's. Anybody have a business license we could use? lol - don't make fun - miracles happen
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