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Millstone

11/06/15 4:50 PM

#31583 RE: WolfWayne #31570

I think it is very bullish if a significant majority showed improvement at 12 weeks versus a simple majority at 5 weeks. What we don't know right now is:

1. The amount of improvement in the MMSE score (how many points?);
2. What the dosages of A2-73 were and what number of the patients were on Aricept + A2-73? Since the dosage was not optimized at 5 weeks, was the significant improvement at 12 weeks as a result of dosage optimization, continued improvement at the same dosage across all patients, or both?

Millstone