Dr. Missling cited a UBS study of the AD "market as big as $13 billion to $67 billion" in his presentation to the OneMed Forum 8 on January 13. The Webcast link is on the company website; see slide 7. That's a big range.
Also the Alzheimer's market is estimated to be worth $20 billion, according to Margaret Patrick reporting on "The Market's Response to Biogen's and Eli Lilly's Alzheimer's Drugs" at the Alzheimer's Association International Conference on July 22. (article in news releases of July 28).
AVXL valuation is also affected to some extent by the full range of indications in the rich pipeline, shown on the Co. website. Enough for now to note that future development and trials will require more funds, so the 162 million outstanding shares will likely march toward the authorized 400 million shares. Plenty of room for speculation -- so much potential and so many unknowns.