IMHO, HE reimbursement price resolution might be completed very quickly after the 1st interim efficacy IA, and the 1st interim efficacy IA has likely taken longer to reach than most anticipated. Just my sense of things.
The first interim efficacy IA occurs at/after 149 progression events. 149 events is 60% of 248. Note: 149 events represents only 43% of the eventual total number of patients from both arms combined. The placebo group makes up 33.3% of the eventual number of patients from that eventual total number.