Direct doesn't "save" anyone until they actually prove it so quit stating otherwise.
I have lived it with my parents. Have you? What you "doubt" is what I actually know for a fact but because it doesn't coincide with your sketcky agenda makes it untrue.
These people who are in hospice AT HOME for the last month are not getting biopsies. How do you think a trial site is going to record a biopsy taken at home and transported to a hospital? They aren't.