Replies to post #191171 on Avid Bioservices Inc (CDMO)

[BKT]

Bio,

I like the way you have been hammering the PS links. Interesting to me is what stranglehold do we actually have on PS technology and the patents that go with it? If it is as strong as we think, then the value of this company is astronomical based upon that alone.

How about connecting some dots with the significance of those patents and how they will effect big pharma. Speaking of big pharma and patents and the expiration of patents and the effect of the percentages of revenue lost, jobs lost and strategies of big pharmas now, was reading this article this morning. Maybe it has been posted before, but if not it is a great read in lay mans terms. 90 pages with charts and graphs . A real eye opener that everyone should read.

http://www.bioassociate.com/wp-content/uploads/2012/05/Bioassociate-The-significance-and-apparent-reprecussions-of-the-2009-2015-pharmaceutical-patent-cliff.pdf

[Protector]

biopharm, I think surgery in general, including all kinds of transplants, would benefit from Bavituximab under the current version of the MOA.

Pre- and post operative application. In the end, if we simplify it to its essence, what is surgery from an immune system's perspective?

It is DAMAGING of cells physically/mechanically (cutting), massively where the cuts are (so localized). Cell damage=release/exposure of PS. Phosphatidylserine (PS) suppresses the dendric cells and macrophages signalling for immune system activation support. That is no different as when the PS gets exposed due to chemo, radio or immuno therapies or by natural or programmed cell death or by any viral attack.

Hence healing is slow and infections (because the dendric cells are affected too) can flourish.

And what are the biggest problems with surgery once the patient is awake again? Right, the risk for infections.

So pre- and post treat patients with Bavituximab, daily (which with important operations isn't an issue because you'll remain in the hospital anyway), with an adequately researched dosage.

[4OurRetirement]

Thanks, Many Future Possible Bavi Beneficial Uses! Glta,eom.