The articles I posted do not show up well on phones I just checked Review on your computer please
There is an established process where the data monitoring committee reviews the progress of the study It is FDA standard procedure to not run a pIII to the end if the data shows real improvement over the comparator ... It is considered unethical in oncology cases
The only reasons to run it to the end is if the data is just so so and you need the numbers to see the significance
The links I provided explains in detail those rules
By my post I am assuming such significance will be shown