Replies to post #14296 on NorthWest Biotherapeutics Inc (NWBO)

[sentiment_stocks]

Thanks antihama -

I think some of us on this board and others are not as medically savvy as others on this board who's careers have been in medicine.

So for my part, understanding what an open unblinded trial versus a closed blinded trial is pretty narrow. Sounds like a closed trial doesn't really exist - to start with - from what I understand you are saying antihama.

I had thought then, that having an "open label (?)" trial meant that as NWBO was made aware of how the Direct trial was progressing, so too would the stockholders and the general public. Which seemed to be exactly what NWBO was doing in informing us of the ongoing progress of the Direct trial.

I had thought that conducting an unblinded trial meant more than just the poor person on the placebo side not knowing whether he was on the placebo or not. In fact, is there even a placebo side to this trial? So it was my understanding (perhaps in error) that having the trial unblinded meant that we are unblinded to the results at any given time.

So when you get back to your computer with the good definitions, it would be helpful to post something that does explain exactly what the difference between the Direct trial is - open label unblinded (?) - and L and others like it - blinded (close labeled?). Sorry, the vernacular is confusing.

What I'm trying to get at is whether NWBO is actually conducting themselves in the proper manner by updating the public because the trial was set up in a manner that allowed them to do that very thing - or not. It doesn't matter to me how other pharmaceutical companies do it - who really cares? What's important is ascertaining that NWBO is doing exactly what the parameters of the trial allow. If that's the case, then I think we are all perfectly justified in rallying behind NWBO in this matter. Thanks again for your help antihama. :)