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Reefrad

05/30/14 4:57 PM

#11907 RE: gnawkz #11903

Yes, BUT, we dont know the enrollment pace since december... If they have been enrolling at a fast pace than its a good sign. However if they have been having enrollment difficulties we would expect a delay in reaching the 2nd interim as well.
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Evaluate

05/30/14 9:34 PM

#11933 RE: gnawkz #11903

I do not think it is that simple.

If most of the events are occurring in the placebo group rather than the treated group, then I think that arriving at the 88 events sooner could be more statistically significant than if the 88 events do not occur for a longer period of time.
In other words, if many of the placebo group patients are experiencing short PFS and few of the patients in the treatment group are experiencing any events, then I think this would bode well for DCVax-L efficacy.