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Astavakra

05/29/14 3:02 PM

#11766 RE: gnawkz #11746

This article is well-worth reading. Thanks for posting.
Here's the gist:

Sometimes Size Doesn't Matter: Reevaluating RECIST and Tumor Response Rate Endpoints

Rabiya S. Tuma

If you give a cancer patient a drug and then the tumor's growth screeches to a halt or a hole appears in its middle, most people would say the drug was working. But on the basis of the response criteria most widely used for solid tumors, these changes mean nothing.
Journal of the National Cancer Institute