My calcs included overhead rates - OHR can be anywhere from 50% to 250% (I've seen the high end personally via contracts I used to monitor). So a drug rep making $65k salary, adding in back office support, utilities, insurance, retirement benefits, everything needed to actually run the company (minus R-IT costs, separate line item), on the bottom line will cost them anywhere from $97.5k to $162.5k per rep - though the latter not likely in this sector. This is why GIA is so frigging expensive for startup biotechs - overhead rates for their own sales force eats up big chunks of revs. The peanuts AMRN is paying for print ads is nothing - Eisai is airing TV ads for ARNA's Belviq, picking cable shows likely to be watched by women for the most part, and they'd aired something like 200 ads for only $50k.