NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

Busy weekend. Let me chime in on the immune system question. I'm not going to post research right now (but I have in the past and could post a lot more).

Here is the Reader's Digest version.

GBM patients typically have compromised immune systems even before they receive chemoradiation. Temador is an interesting chemo drug in that it is one of the only chemotherapies that makes it through the blood brain barrier. Fortunately, unlike Glidel wafers, it takes a long time for Temador to destroy the immune system (Glidel wafers do it quickly when it is placed directly into the brain. Despite the best intentions of the person who created this therapy, it truly is a barbaric and horribly abusive treatment for brain cancer patients.) Because it takes a long time for Temador to nearly destroy the immune system, and because Temador is given in several week series followed by breaks; the fact that dendritic therapy helps restore the immune system, and due to the fact the tumor progression itself happens relatively quickly in placebo patients, I personally do not believe this should be an issue that keeps people up at night.