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biomaven0

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biomaven0

Re: biomaven0 post# 175743

Thursday, 03/20/2014 2:50:41 PM

Thursday, March 20, 2014 2:50:41 PM

Post# of 252526
Bottom line here was the sensitivity of the DNA test was an absolute difference of 20% better than FIT for cancer or advanced pre-cancer. The AUC of the ROC was indeed better too - 0.94 vs. 0.89 for CRC and 0.73 vs 0.67 for advanced neoplasia (the latter had p<.001). Net was an increase of 78% in detection of advanced precancerous lesions compared with FIT.

http://www.nejm.org/doi/pdf/10.1056/NEJMoa1311194
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