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Re: BioInfo post# 4584

Wednesday, 02/19/2014 11:08:43 AM

Wednesday, February 19, 2014 11:08:43 AM

Post# of 700533
Going into early 2011, we had 33 patients who may or may or may not have had an event by then. They'd all likely have been in the trial for 36 months by 2011. Let's just ballpark that at 25 events through today.

That means from the time enrollment restarted in early 2011 to December 2013 (aka: about 3 years), it took 36 months to obtain the additional 41 events -- or 13.66 events per year.

Of course that is when enrollment was ramping up. Moreover, there was a few month window in the first half of 2011 where very few, if any, events occurred.

The next interim review would be triggered by 22 more events from December 10, 2013.

With enrollment now both continuous and faster, I'd say the events per year probably is now somewhere between 22 and 30, but that may be conservative because NWBO really increased the number of clinics over the past 18 months.

Anyway, I'd speculate late summer to late fall.





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