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Re: f3tt3f post# 4394

Thursday, 02/13/2014 12:56:56 AM

Thursday, February 13, 2014 12:56:56 AM

Post# of 700545
Just my 2 cents….I'll explain my thinking more tomorrow, but research concludes the mesenchymal subgroup also responds well (not as well as it does to DCVAX) to "aggressive" chemo/radiation therapy. The key in the present DCVAX-L trial is that all tumors at baseline are stable due to trial design, and DCVAX-L has an overall more synergistic effect in this case. Regardless, IMHO, even if the trial design did not have the above feature, we'd still meet the endpoints.
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